Influence of aging on peripheral nerve function and regeneration

This manuscript provides a comprehensive review of how aging affects peripheral nerve function and regeneration. The authors have done a thorough job of summarizing the current literature on this topic.

• Comprehensive coverage of the topic
• Well-structured presentation of the material
• Clear figures that illustrate key concepts
• Balanced discussion of conflicting evidence

• Some recent studies (2023-2025) are not included
• The section on clinical implications could be expanded
• The discussion of potential therapeutic approaches is limited

• The authors should consider including more recent studies, particularly those published in the last two years.
• The section on clinical implications should be expanded to include more discussion of how these findings might translate to clinical practice.
• The discussion of potential therapeutic approaches is currently limited. This section could be expanded to include more discussion of emerging therapies.

• There are a few typographical errors throughout the manuscript.
• Some of the figures could be improved for clarity.
• The reference formatting is inconsistent in places.